WHAT'S NEW AT LRI
What Can Speed New Lupus Treatments?
We thought you’d like to know about some compelling ideas on using new technologies to move incredible LRI discoveries from the laboratory to patient care—and quickly.
Researchers, NIH leaders, pharmaceutical and biotechnology experts, technology innovators from other fields—all were wowed by technology advances presented at the LRI's Forum for Discovery scientific conference.
LRI at the Forefront of Advancing Innovation
Experts at the conference’s special industry panel said that cutting-edge technologies in systems biology are producing great opportunities to actually fast-forward human studies in lupus and autoimmunity.
Technology Speeding Answers on Lupus
"How can the new technologies actually help speed treatments?"
Here are just a few ways, the panelists offered:
Gregory Dennis, MD, Human Genome Sciences:
“Using systems modeling to predict immunological responses is fascinating. It suggests that one day it might be possible to perform more informative proof-of-concept studies to assess immune targets prior to performing clinical trials.”
Paul Brunetta, MD, Genentech:
“It’s an incredibly exciting time. Right now, I’d say the most important thing that we can do is really to focus mostly on the instrument we use to measure the effectiveness of a new treatment or approach.”
Implications for Human Lupus Biology
The new technologies also supply rocket fuel to the LRI’s recently launched program in the biology of human lupus—using tiny amounts of human material (cells, blood, tissue), rather than animals, to generate new answers applicable to the human disease.
“The potential now to leap-frog rapidly from animal models to understanding human systems is nothing less than stunning,” said LRI President Margaret Dowd.
The Industry Panel
(l to r): Paul Brunetta, MD, Genentech; Matthew D. Linnik, PhD, La Jolla Pharmaceuticals; Gregory Dennis, MD, Human Genome Sciences; Marcus Clark, MD, University of Chicago; Benjamin D. Schwartz, MD, PhD, Washington University School of Medicine.
(also pictured, lower left: Greg E. Lemke, PhD, Salk Institute)
About the LRI
Lupus Research Institute