Discovery: Pioneering discovery to prevent, treat and cure lupus
July 2009

What's New at LRI

Funding for Lupus Discoveries
Tops $70 Million

Our innovative ideas keep winning new support at the NIH

Despite tough economic times, the LRI model of backing bold ideas in lupus is going strong and proving successful at securing even larger long-term funding.

It was just last fall that we told you about the $60 million that LRI researchers had leveraged at the NIH and other organizations.

Now it’s $10 million more—$70 million—from the $26 million that the families and friends of people with lupus who founded the LRI have put in to finding ways to prevent, treat, and cure this complex disease. And it’s a leverage figure likely to rise even more, as many of the investigators are not even half way through their 3-year grants!

Building Momentum

Part of this recent $10 million is going to LRI researcher Marcus Clark, MD, at the University of Chicago.

He recently got the news that the NIH had selected the university’s Gwen Knapp Center for Lupus and Immunology Research, which he co-directs, as an “Autoimmunity Center of Excellence.” The $4.2 million will help Dr. Clark and his team to dig deeper in to solutions to lupus. More  

New funding is also keeping alive the innovative work of Thereza Imanishi-Kari, PhD, at the Tufts University School of Medicine in Boston, whose LRI grant ended this year.

Now with $300,000 from the NIH’s National Institute of Allergy and Infectious Diseases, she will be able to continue mining her data on why the lupus immune system makes a basic mistake and fails to recognize its real enemies, turning on the body it is supposed to defend. More 

And at the beginning of this month, Jochen Mattner, MD, at Cincinnati Children’s Hospital Medical Center will start getting payments from his 5-year, $1.875 million NIH grant to further explore the novel hypothesis that he first examined with LRI support.

Dr. Mattner’s idea: that certain bacterial or viral infections might elicit strong immune responses that in turn prompt autoimmune illnesses such as lupus. With compelling evidence in hand, he’ll now see if straightforward antibiotic treatments can prevent or halt the autoimmune process in genetically susceptible individuals. More

Others Who’ve Recently Won Funding:

Chau-Ching Liu, MD, PhD, at the University of Pittsburgh School of Medicine has won an NIH grant of $1.2 million to continue the research that she began with us.

Inez Rogatsky, PhD, at the Hospital for Special Surgery in New York has won a Kirkland Center Research Grant for $60,000 to continue the research that she began with us.

A trio of LRI researchers—Martin Weigert, PhD, at the University of Chicago, Zhixin Zhang, PhD, at the University of Nebraska in Omaha, and Marko A. Radic, PhD, at the University of Tennessee—has secured a $600,000 grant from the Dana Foundation to continue work initiated through collaborations with us.

Root Them On!

Half a country away, at a Los Angeles fundraiser, Debbi Cowan movingly described the dream that this kind of research adds up to for her daughter, 23-year-old Amanda, who struggles with lupus.

“My dream for my daughter,” she said, “is that one day she will wake up and she will be able to look forward to a future that is as beautiful and exciting as she can imagine….A life filled with promise. And until that day we will never stop working to make it so.” Watch the video on YouTube. 

Broadcast Your Dream for Lupus Research

Help us support more innovative lupus research—and if you’d like, also tell us about your dream for the future. Email and we’ll post your comments on our Web site! 

Donate Today

Run the NYC Marathon this November with Team Life Without Lupus!

The S.L.E. Lupus Foundation is fielding the first-ever Team Life Without Lupus in this year’s ING New York City Marathon.

The Foundation is offering guaranteed spots to runners around the country committed to fundraising for lupus research!

Applications accepted through July 6th.

Get the details – and tell your friends!





Now accepting applications for 
Team Life Without Lupus in the ING New York City Marathon on November 1, 2009.

About the LRI
The nation’s only nonprofit singularly dedicated to novel research in lupus, we champion innovation and scientific risk-taking in the hunt for solutions to this complex and dangerous autoimmune disease.

Lupus Research Institute
330 Seventh Avenue, Suite 1701, New York, NY 10001
T: 212.812.9881 F: 212.545.1843