Lupus Research Institute
December 2007
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Lupus Research Institute (LRI) scientists are making key discoveries in lupus. Read on to find out what they are--and what advances and challenges lie ahead.



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LRI Discoveries Blaze New Paths to Understanding and Treating Lupus
Results Ripple through Field, Transform Research Outlook

In frustration over the glacial pace of discoveries in lupus, families and scientists formed the Lupus Research Institute with the conviction that being open to the most brilliant ideas would finally shake up the field, spur innovation, and generate new understanding of why and how the lupus immune system attacks the body that it should be defending.

Now a professional assessment of the Institute-funded work completed to date reports striking successes for this pioneering approach. In funding ideas that others wouldn't risk--85 new ideas explored over 3 years each--the LRI has energized and advanced immune system research in lupus.

"The speed with which the Institute has changed the outlook for lupus research is remarkable," said William Paul, MD, Chief, Laboratory of Immunology, NIAID-NIH, and Chair of the LRI's Scientific Advisory Board.

Featured Discoveries:
  • Genes that Increase Susceptibility to Lupus
  • How Lupus Damanges Organs--Kidneys, Heart, Brain, Skin
  • Pathways that Enable Misguided Antibodies to Attack
  • Molecules that Determine Control of the Immune System
  • Targets for New Treatments
  • 20+ New Biomarkers for Diagnosing, Monitoring & Treating Lupus
Click here to read a summary of the scope and impact of the discoveries »


New Round of LRI Awards Brings Promise of More Breakthroughs

Recipients of the latest round of highly competitive, 3-year $300,000 grants will be working at the laboratory bench as well as through clinical studies to pursue their unique and powerful hypotheses on why, in lupus, the immune system so tragically turns against the body it is designed to defend.

The 12 scientists awarded 2007 grants are working in the following key areas:

Click to read about each of the new grants at LupusResearchInstitute.org »

Challenges in Translation
Innovation to Clinical Development the Topic at 7th Annual LRI Conference

Janet Woodcock
September 24 - 25, 2007

Panels, Posters and Presentations Foster Idea Exchange and Collaboration at 2-Day Meeting

(Picture at left) Special Dinner Speaker, FDA Deputy Director, Janet Woodcock, MD, explores the challenges in bringing lupus medicines to market.



Special Industry Panel
Special Industry Panel
Moderator, Mary Crow, MD. Participants: Jeff Browning, PhD, of Biogen Idec; Anthony Coyle, PhD, of Medimmune; Rainer Fuchs, PhD, of Biogen Idec; Arthur Krieg, MD, of Coley Pharmaceutical Group; and, (pictured at left) Paul Brunetta, MD, of Genentech and Robert Zivin, PhD, of Johnson & Johnson.




LRI Scientists in discussion
"The key note speaker at dinner and interfacing with pharmaceutical reps at the panel discussion firmly plants our basic science research in the pipeline for drug discovery. It's critical that basic scientists better understand how it all works."

-- LRI Scientist, Marko A. Radic, PhD, University of Tennessee, Memphis



Click here for more »

Thank Congressman Young!
Send Appreciation to Capitol Hill for Lupus Research Victory by December 15th

Congressman Young and Lupus AdvocatesThe LRI is calling on lupus advocates from across the country to gather thank you letters for Congressman Bill Young in appreciation of his work in making the 5-Year Research Plan for Lupus a reality at the National Institutes of Health.

Click here to read about the plan »

Add your voice, write your own letter of appreciation, and encourage Congressman Young and his colleagues to keep up the good work! Let them know how important the commitment to lupus research is to you.

Send your letters to the LRI and we'll deliver them directly to Congressman Young's office in Washington, DC.

Email letters to lstegmaier@lupusny.org or mail to:
T
hank You Congressman Young! c/o Lupus Research Institute
330 Seventh Ave, Suite 1701
New York, NY 10001

Deadline is December 15, 2007


This Holiday Season, Shop for Lupus
ShopForLupus.org

The LRI has launched the only place to shop online where the money you spend will help to find new treatments and a cure for lupus.

For holiday shopping, start at ShopforLupus.org. All of your favorite retailers are there. Just click through to their sites and a percentage of each purchase will go to the LRI.

Start shopping today!
Click to visit ShopforLupus.org »

To ensure that your purchases go to support lupus research, you must click through ShopForLupus.org so that the retailer will credit the referral to us.

There is no additional cost to you or to the Lupus Research Institute.

What better gift can you give than helping your favorite cause?

Have questions? Visit the FAQ page »