Central Nervous System

One of the most feared complications of lupus is central nervous system damage resulting in loss of memory, cognition and attention difficulties, and other neurologic and psychiatric problems.

LRI scientists have made exciting breakthroughs in this area.

One researcher has found evidence that stress hormones may be to blame, as they open up channels for antibodies to cross in to the brain and wreak havoc there.

Betty Diamond, MD
Feinstein Institute for Medical Research
North Shore-LIJ Health System
Class of 2001

Also possible: a cascade of antibody reactions lead to the release of brain-altering proteins.

This LRI researcher is looking into it.

Keith Elkon, MD
University of Washington, Seattle, WA
Class of 2006

Another bold approach: searching for answers through new high-technology imaging tools such as MRIs, to see if brain imaging markers correlate with cognitive dysfunction.

Roland G. Henry, PhD
University of California at San Francisco, CA
Class of 2005

Jane Salmon, MD
Hospital for Special Surgery, New York, NY
Class of 2009

Meggan Mackay, MD
The Feinstein Institute of Medical Research, NY
Class of 2012

Chandra Mohan, MD, PhD
University of Texas Southwestern Medical Center, Dallas, TX
Class of 2013