With funding from the Lupus Research Institute and several other organizations, an international study identified three different genes associated with an increased risk of lupus. Led by Christopher Lessard, PhD at Oklahoma Medical Research, researchers throughout the world collected over 17,000 genetic samples for testing. They found that the genes IRF8, TMEM39a and IKZF3 were markers of increased risk for lupus, but each gene poses risk to different ethnic groups.
According to Dr. Lessard, further understanding how these genes impact the development of lupus could be key to improving diagnosis and treatment. The study is published in The American Journal of Human Genetics.