2 genes are important key to regulating immune response

Pbx-1, Prep-1 help spur IL-10 production; findings have implications for research into lupus, cancer and HIV/AIDS

NEW YORK (Dec. 28, 2007) -- A research team at Weill Cornell Medical College in New York City has identified two genes that may be crucial to the production of an immune system cytokine called interleukin-10 (IL-10).

The discovery fills in an important "missing link" in a biochemical pathway that's long been tied to disorders ranging from lupus and Type 1 diabetes, to cancer and AIDS.

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