Stephen C. Pelsue, PhD
University of Southern Maine, Portland, ME
The genes a person inherits may make him or her more susceptible to lupus.
Researchers have found that defective versions of the newly identified gene, Ttc7, results in a lupus-like autoimmune disease in mice.
With LRI funding, Dr. Pelsue is using sophisticated imaging and analytical tools to better understand this gene and its function in cells of the immune system.
He is using newly created mouse models to clarify how the gene contributes to the production of damaging autoantibodies—and thereby generate key insight into what causes such devastating autoimmune diseases as lupus.
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- B Cells
- Cardiovascular System
- Cell Signaling
- Central Nervous System
- Dendritic Cells
- Environmental Triggers
- Gender Matters
- General Immune System Function
- Human Lupus Biology
- Lupus Pregnancy
- New to Lupus
- New Treatments
- T Cells
- Target Identification
- Why the Lupus Immune System Reacts to Its Own DNA